Present: Per Hyltoft Petersen, Peter Felding, Ari Lahti, Nils Jørgensen,
Pål Rustad
Basis
for most of the discussions (sorry that this is in Norwegian):
Correction
generally
Peter
suggested to use target for X as correction factor for all series with
X. Have to look at possible method differences for factor between CAL
and X.
Target
CAL.
Decided
to use reference method values for all components if they exist. Split
creatinin in two method groups, enzymatic and Jaffe methods. Ref. values
for creatinin should only be used for enzymatic methods, for Jaffe
target value from project.
Use
correction also for enzymes.
Analytical
quality
Suggestion
to include measurement uncertainty into quality goals by Per H accepted,
and the formula suggested by Pål accepted with the modification by
using z=1.65 instead of z=1.96. Ari suggested to use measurement
uncertainty function to calculate quality goal for quotients. Ari and Pål
discuss this further, but have only academic interest (look beneath).
Calculations
show that elimination of reference values by suggested quality goals
have limited influence on calculated reference intervals for the
majority of components (except for instance Na, albumin). This means
that all results can be included for many components which is important
to make the subgroups as large as possible.
Elimination
of persons with abnormal values
Decided
that we use the criteria:
One
value outside 5 s
Two
values outside 4 s
s
is calculated as logarithmic s for all components i.e. s = (lnH - lnL)/4
with reference M=(lnH+lnL)/2.
Peter
will judge the reference values for each person before the person is
eliminated from the data pool.
Primary
subgroup categories
Gender,
age, fasting, sample collection time
Oestrogen:
Compare oestrogen group with non oestrogen group instead of all against
non oestrogen group.
Iceland
Per
will produce a new workshop program with theory before lunch and NORIP
results after lunch.
Heidi
is asked to talk about practical aspects of introducing new reference
intervals in the laboratory.
Per
S is asked to look at the enzymes
Can
Arne be stand in for Leifur to summarise practical problems for the
laboratories to carry out the project?
Home
site
Decided
to publish results as they are produced on the project web home site –
shall be the basis of a questionnaire to the participants of the
workshop to get questions for the workshop.
Publishing
SJCLI
special issue and extract to CCLM.
Pål
Rustad
25.3.2002