Basic data on CAL

NORIP Traceability

Component	CAL Calibrator used in NORIP	NFKK Reference Serum X Certificate of analysis	Measurement methods
Alanine transaminase (ALT)	DGKC 19971	Transferred value from CAL in NORIP	IFCC Reference method at 37°C
Alkaline phosphatase (ALP)	NORIP consensus	NORIP, consensus	IFCC 37°C compatible method (Roche Modular and Ortho Vitros)
Albumin	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	RID (radial immune diffusion), Reference material: CRM 470
Amylase	NORIP consensus	NORIP, consensus	IFCC 37°C compatible method
Amylase, pancreatic	NORIP consensus	NORIP, consensus	IFCC 37°C compatible method
Aspartate transaminase (AST)	NORIP consensus	NORIP, consensus	IFCC 37°C compatible method
Bilirubins	DGKC 19971	NORIP CAL, transferred	Jendrassik
Calcium	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Cholesterol	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Creatine kinase (CK)	DGKC 19971	Transferred value from CAL in NORIP	IFCC Reference method at 37°C
Creatinine	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Gamma- glutamyltransferase (GT)	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IFCC Reference method at 37°C
Glucose	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
HDL cholesterol	NORIP consensus	NORIP, consensus	Direct methods
Iron	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Lactate dehydrogenase (LD)	NORIP consensus	NORIP, consensus	IFCC 37°C compatible method (Roche Modular)
Magnesium	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Phosphate	DGKC 19971	Transferred value from CAL in NORIP	Ion chromatography, scintillation count
Potassium	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Protein	DGKC 19971	NORIP CAL, transferred	Biuret (Doumas et. al.)
Sodium	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Gravimetry, FAES (flame atomic emission spectrometry)
Total iron binding capacity (TIBC))	NORIP consensus	NORIP, consensus	Transferrin methods [g/L] with IFCC calibration with factor 25.1 µmol/g to TIBC [µmol/L]
Triglycerides	DGKC 19971	Transferred value from CAL in NORIP	GC/IDMS (gas chromatography/isotope dilution mass spectrometry)
Urate	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)
Urea (carbamide)	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	Transferred from IMEP 17 Material 12 in Nordic Trueness Project3	IDMS (isotope dilution mass spectrometry)

1. DGKC 1997

Consensus Mean and Reference Measurement values in an EQA Scheme, Uldall, A et. al., EQA News, 1998, 9 no 3

Page 1, page 2, page 3

2. IMEP 17, Material 1

Örnemark U, Uldall A, Van Nevel L, Aregbe Y, Taylor P.D.P. IMEP-17, Trace and Minor Constituents in Human Serum. Certification Report.

3. Nordic Trueness Project

Pedersen MM et al. The Nordic Trueness Project 2002: use of reference measurement procedure values in a general clinical chemistry survey. Scand J Clin Lab Invest 2004; 64: 309-320

NORIP data

Basic project data on CAL

Descriptive NORIP statistics on CAL by instrument producer (8/2-2002)

Descriptive NORIP statistics on CAL by method group (12/12-2002)

Comparison of transfer of CAL data to X in NORIP and in Nordic Trueness project (13/12-2002)